Genetic Variation at the LDL Receptor and HMG CoA Reductase Gene Loci, Lipid Levels, Statin Response, and Cardiovascular Disease Incidence in PROSPER

Our purpose was to evaluate associations of single nucleotide polymorphisms (SNPs) at the low density lipoprotein (LDL) receptor (LDLR C44857T, minor allele frequency (MAF) 0.26, and A44964G, MAF 0.25, both in the untranslated region) and HMG-CoA reductase (HMGCR i18T>G, MAF 0.019) gene loci with...

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Detalhes bibliográficos
Publicado no:Atherosclerosis
Main Authors: Polisecki, Eliana, Muallem, Hind, Maeda, Nobuyo, Peter, Inga, Robertson, Michele, McMahon, Alex D, Ford, Ian, Packard, Christopher, Shepherd, James, Jukema, J Wouter, Westendorp, Rudi G. J., de Craen, Anton J. M., Buckley, Brendan M., Ordovas, Jose M., Schaefer, Ernst J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4565152/
https://ncbi.nlm.nih.gov/pubmed/18261733
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.atherosclerosis.2007.12.004
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