Cholesterol absorption and synthesis markers in individuals with and without a CHD event during pravastatin therapy: insights from the PROSPER trial

Cholesterol homeostasis, defined as the balance between absorption and synthesis, influences circulating cholesterol concentrations and subsequent coronary heart disease (CHD) risk. Statin therapy targets the rate-limiting enzyme in cholesterol biosynthesis and is efficacious in lowering CHD events...

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Detalhes bibliográficos
Main Authors: Matthan, Nirupa R., Resteghini, Nancy, Robertson, Michele, Ford, Ian, Shepherd, James, Packard, Chris, Buckley, Brendan M., Jukema, J. Wouter, Lichtenstein, Alice H., Schaefer, Ernst J.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Biochemistry and Molecular Biology 2010
Assuntos:
Patient-Oriented and Epidemiological Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2789780/
https://ncbi.nlm.nih.gov/pubmed/19578163
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M900032-JLR200
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