Cholesterol absorption and synthesis markers in individuals with and without a CHD event during pravastatin therapy: insights from the PROSPER trial

Cholesterol homeostasis, defined as the balance between absorption and synthesis, influences circulating cholesterol concentrations and subsequent coronary heart disease (CHD) risk. Statin therapy targets the rate-limiting enzyme in cholesterol biosynthesis and is efficacious in lowering CHD events...

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Autors principals: Matthan, Nirupa R., Resteghini, Nancy, Robertson, Michele, Ford, Ian, Shepherd, James, Packard, Chris, Buckley, Brendan M., Jukema, J. Wouter, Lichtenstein, Alice H., Schaefer, Ernst J.
Format: Artigo
Idioma:Inglês
Publicat: The American Society for Biochemistry and Molecular Biology 2010
Matèries:
Patient-Oriented and Epidemiological Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2789780/
https://ncbi.nlm.nih.gov/pubmed/19578163
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M900032-JLR200
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