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Reverse engineering of logic-based differential equation models using a mixed-integer dynamic optimization approach
Motivation: Systems biology models can be used to test new hypotheses formulated on the basis of previous knowledge or new experimental data, contradictory with a previously existing model. New hypotheses often come in the shape of a set of possible regulatory mechanisms. This search is usually not...
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| Publié dans: | Bioinformatics |
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| Auteurs principaux: | , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Oxford University Press
2015
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4565031/ https://ncbi.nlm.nih.gov/pubmed/26002881 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btv314 |
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