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A parallel metaheuristic for large mixed-integer dynamic optimization problems, with applications in computational biology

BACKGROUND: We consider a general class of global optimization problems dealing with nonlinear dynamic models. Although this class is relevant to many areas of science and engineering, here we are interested in applying this framework to the reverse engineering problem in computational systems biolo...

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Bibliografische gegevens
Gepubliceerd in:PLoS One
Hoofdauteurs: Penas, David R., Henriques, David, González, Patricia, Doallo, Ramón, Saez-Rodriguez, Julio, Banga, Julio R.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2017
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5557587/
https://ncbi.nlm.nih.gov/pubmed/28813442
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0182186
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