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Data-driven reverse engineering of signaling pathways using ensembles of dynamic models

Despite significant efforts and remarkable progress, the inference of signaling networks from experimental data remains very challenging. The problem is particularly difficult when the objective is to obtain a dynamic model capable of predicting the effect of novel perturbations not considered durin...

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Vydáno v:PLoS Comput Biol
Hlavní autoři: Henriques, David, Villaverde, Alejandro F., Rocha, Miguel, Saez-Rodriguez, Julio, Banga, Julio R.
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5319798/
https://ncbi.nlm.nih.gov/pubmed/28166222
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1005379
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