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Data-driven reverse engineering of signaling pathways using ensembles of dynamic models

Despite significant efforts and remarkable progress, the inference of signaling networks from experimental data remains very challenging. The problem is particularly difficult when the objective is to obtain a dynamic model capable of predicting the effect of novel perturbations not considered durin...

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Publicat a:PLoS Comput Biol
Autors principals: Henriques, David, Villaverde, Alejandro F., Rocha, Miguel, Saez-Rodriguez, Julio, Banga, Julio R.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5319798/
https://ncbi.nlm.nih.gov/pubmed/28166222
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1005379
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