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Integrating literature-constrained and data-driven inference of signalling networks

Motivation: Recent developments in experimental methods facilitate increasingly larger signal transduction datasets. Two main approaches can be taken to derive a mathematical model from these data: training a network (obtained, e.g., from literature) to the data, or inferring the network from the da...

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Detalhes bibliográficos
Main Authors: Eduati, Federica, De Las Rivas, Javier, Di Camillo, Barbara, Toffolo, Gianna, Saez-Rodriguez, Julio
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3436796/
https://ncbi.nlm.nih.gov/pubmed/22734019
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/bts363
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