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Leucine modulates dynamic phosphorylation events in insulin signaling pathway and enhances insulin-dependent glycogen synthesis in human skeletal muscle cells

BACKGROUND: Branched-chain amino acids, especially leucine, are known to interact with insulin signaling pathway and glucose metabolism. However, the mechanism by which this is exerted, remain to be clearly defined. In order to examine the effect of leucine on muscle insulin signaling, a set of expe...

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Detalhes bibliográficos
Main Authors: Di Camillo, Barbara, Eduati, Federica, Nair, Sreekumaran K, Avogaro, Angelo, Toffolo, Gianna M
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3994550/
https://ncbi.nlm.nih.gov/pubmed/24646332
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2121-15-9
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