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Leucine modulates dynamic phosphorylation events in insulin signaling pathway and enhances insulin-dependent glycogen synthesis in human skeletal muscle cells

BACKGROUND: Branched-chain amino acids, especially leucine, are known to interact with insulin signaling pathway and glucose metabolism. However, the mechanism by which this is exerted, remain to be clearly defined. In order to examine the effect of leucine on muscle insulin signaling, a set of expe...

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Détails bibliographiques
Auteurs principaux: Di Camillo, Barbara, Eduati, Federica, Nair, Sreekumaran K, Avogaro, Angelo, Toffolo, Gianna M
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2014
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3994550/
https://ncbi.nlm.nih.gov/pubmed/24646332
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2121-15-9
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