Generation of gene-modified goats targeting MSTN and FGF5 via zygote injection of CRISPR/Cas9 system

Recent advances in the study of the CRISPR/Cas9 system have provided a precise and versatile approach for genome editing in various species. However, the applicability and efficiency of this method in large animal models, such as the goat, have not been extensively studied. Here, by co-injection of...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Sci Rep
Hauptverfasser: Wang, Xiaolong, Yu, Honghao, Lei, Anmin, Zhou, Jiankui, Zeng, Wenxian, Zhu, Haijing, Dong, Zhiming, Niu, Yiyuan, Shi, Bingbo, Cai, Bei, Liu, Jinwang, Huang, Shuai, Yan, Hailong, Zhao, Xiaoe, Zhou, Guangxian, He, Xiaoling, Chen, Xiaoxu, Yang, Yuxin, Jiang, Yu, Shi, Lei, Tian, Xiue, Wang, Yongjun, Ma, Baohua, Huang, Xingxu, Qu, Lei, Chen, Yulin
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2015
Schlagworte:
Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4564737/
https://ncbi.nlm.nih.gov/pubmed/26354037
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep13878
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge