Disruption of FGF5 in Cashmere Goats Using CRISPR/Cas9 Results in More Secondary Hair Follicles and Longer Fibers

Precision genetic engineering accelerates the genetic improvement of livestock for agriculture and biomedicine. We have recently reported our success in producing gene-modified goats using the CRISPR/Cas9 system through microinjection of Cas9 mRNA and sgRNAs targeting the MSTN and FGF5 genes in goat...

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Publicat a:PLoS One
Autors principals: Wang, Xiaolong, Cai, Bei, Zhou, Jiankui, Zhu, Haijing, Niu, Yiyuan, Ma, Baohua, Yu, Honghao, Lei, Anmin, Yan, Hailong, Shen, Qiaoyan, Shi, Lei, Zhao, Xiaoe, Hua, Jinlian, Huang, Xingxu, Qu, Lei, Chen, Yulin
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2016
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5068700/
https://ncbi.nlm.nih.gov/pubmed/27755602
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0164640
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