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High-throughput determination of RNA structure by proximity ligation

We present an unbiased method to globally resolve RNA structures through pairwise contact measurements between interacting regions. RNA Proximity Ligation (RPL) uses proximity ligation of native RNA followed by deep sequencing to yield chimeric reads with ligation junctions in the vicinity of struct...

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Detaylı Bibliyografya
Yayımlandı:Nat Biotechnol
Asıl Yazarlar: Ramani, Vijay, Qiu, Ruolan, Shendure, Jay
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2015
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4564351/
https://ncbi.nlm.nih.gov/pubmed/26237516
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nbt.3289
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