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High-throughput determination of RNA structure by proximity ligation

We present an unbiased method to globally resolve RNA structures through pairwise contact measurements between interacting regions. RNA Proximity Ligation (RPL) uses proximity ligation of native RNA followed by deep sequencing to yield chimeric reads with ligation junctions in the vicinity of struct...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Nat Biotechnol
मुख्य लेखकों: Ramani, Vijay, Qiu, Ruolan, Shendure, Jay
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: 2015
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC4564351/
https://ncbi.nlm.nih.gov/pubmed/26237516
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nbt.3289
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