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Highly Efficient Ligation of Small RNA Molecules for MicroRNA Quantitation by High-Throughput Sequencing

MiRNA cloning and high-throughput sequencing, termed miR-Seq, stands alone as a transcriptome-wide approach to quantify miRNAs with single nucleotide resolution. This technique captures miRNAs by attaching 3’ and 5’ oligonucleotide adapters to miRNA molecules and allows de novo miRNA discovery. Coup...

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Bibliografiske detaljer
Udgivet i:J Vis Exp
Main Authors: Lee, Jerome E., Yi, Rui
Format: Artigo
Sprog:Inglês
Udgivet: MyJove Corporation 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4354015/
https://ncbi.nlm.nih.gov/pubmed/25490151
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/52095
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