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Effects of Exercise on Progranulin Levels and Gliosis in Progranulin-Insufficient Mice1,2,3
Loss-of-function mutations in progranulin (GRN) are one of the most common genetic causes of frontotemporal dementia (FTD), a progressive, fatal neurodegenerative disorder with no available disease-modifying treatments. Through haploinsufficiency, these mutations reduce levels of progranulin, a prot...
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| Pubblicato in: | eNeuro |
|---|---|
| Autori principali: | , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Society for Neuroscience
2015
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4562684/ https://ncbi.nlm.nih.gov/pubmed/26361634 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/ENEURO.0061-14.2015 |
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