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Diet-induced obesity promotes altered remodeling and exacerbated cardiac hypertrophy following pressure overload

Heart failure (HF) is the end stage of cardiovascular disease, in which hypertrophic remodeling no longer meets cardiac output demand. Established animal models of HF have provided insights into disease pathogenesis. However, these models are developed on dissimilar metabolic backgrounds from humans...

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Publicado en:Physiol Rep
Main Authors: Holzem, Katherine M, Marmerstein, Joseph T, Madden, Eli J, Efimov, Igor R
Formato: Artigo
Idioma:Inglês
Publicado: John Wiley & Sons, Ltd 2015
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4562575/
https://ncbi.nlm.nih.gov/pubmed/26290533
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14814/phy2.12489
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