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Diet-induced obesity promotes altered remodeling and exacerbated cardiac hypertrophy following pressure overload

Heart failure (HF) is the end stage of cardiovascular disease, in which hypertrophic remodeling no longer meets cardiac output demand. Established animal models of HF have provided insights into disease pathogenesis. However, these models are developed on dissimilar metabolic backgrounds from humans...

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Detalhes bibliográficos
Publicado no:Physiol Rep
Main Authors: Holzem, Katherine M, Marmerstein, Joseph T, Madden, Eli J, Efimov, Igor R
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley & Sons, Ltd 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4562575/
https://ncbi.nlm.nih.gov/pubmed/26290533
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14814/phy2.12489
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