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Loss of Akap1 Exacerbates Pressure Overload-Induced Cardiac Hypertrophy and Heart Failure

Left ventricular hypertrophy (LVH) is a major contributor to the development of heart failure (HF). Alterations in cyclic adenosine monophosphate (cAMP)-dependent signaling pathways participate in cardiomyocyte hypertrophy and mitochondrial dysfunction occurring in LVH and HF. cAMP signals are recei...

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發表在:Front Physiol
Main Authors: Schiattarella, Gabriele G., Boccella, Nicola, Paolillo, Roberta, Cattaneo, Fabio, Trimarco, Valentina, Franzone, Anna, D’Apice, Stefania, Giugliano, Giuseppe, Rinaldi, Laura, Borzacchiello, Domenica, Gentile, Alessandra, Lombardi, Assunta, Feliciello, Antonio, Esposito, Giovanni, Perrino, Cinzia
格式: Artigo
語言:Inglês
出版: Frontiers Media S.A. 2018
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5985454/
https://ncbi.nlm.nih.gov/pubmed/29892230
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2018.00558
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