Loss of Akap1 Exacerbates Pressure Overload-Induced Cardiac Hypertrophy and Heart Failure

Left ventricular hypertrophy (LVH) is a major contributor to the development of heart failure (HF). Alterations in cyclic adenosine monophosphate (cAMP)-dependent signaling pathways participate in cardiomyocyte hypertrophy and mitochondrial dysfunction occurring in LVH and HF. cAMP signals are recei...

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Bibliografske podrobnosti
izdano v:Front Physiol
Main Authors: Schiattarella, Gabriele G., Boccella, Nicola, Paolillo, Roberta, Cattaneo, Fabio, Trimarco, Valentina, Franzone, Anna, D’Apice, Stefania, Giugliano, Giuseppe, Rinaldi, Laura, Borzacchiello, Domenica, Gentile, Alessandra, Lombardi, Assunta, Feliciello, Antonio, Esposito, Giovanni, Perrino, Cinzia
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2018
Teme:
Physiology
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5985454/
https://ncbi.nlm.nih.gov/pubmed/29892230
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2018.00558
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