Loss of Akap1 Exacerbates Pressure Overload-Induced Cardiac Hypertrophy and Heart Failure

Left ventricular hypertrophy (LVH) is a major contributor to the development of heart failure (HF). Alterations in cyclic adenosine monophosphate (cAMP)-dependent signaling pathways participate in cardiomyocyte hypertrophy and mitochondrial dysfunction occurring in LVH and HF. cAMP signals are recei...

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Foilsithe in:Front Physiol
Main Authors: Schiattarella, Gabriele G., Boccella, Nicola, Paolillo, Roberta, Cattaneo, Fabio, Trimarco, Valentina, Franzone, Anna, D’Apice, Stefania, Giugliano, Giuseppe, Rinaldi, Laura, Borzacchiello, Domenica, Gentile, Alessandra, Lombardi, Assunta, Feliciello, Antonio, Esposito, Giovanni, Perrino, Cinzia
Formáid: Artigo
Teanga:Inglês
Foilsithe: Frontiers Media S.A. 2018
Ábhair:
Physiology
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5985454/
https://ncbi.nlm.nih.gov/pubmed/29892230
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2018.00558
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