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Dose-schedule finding in phase I/II clinical trials using a Bayesian isotonic transformation
A dose-schedule-finding trial is a new type of oncology trial in which investigators aim to find a combination of dose and treatment schedule that has a large probability of efficacy yet a relatively small probability of toxicity. We demonstrate that a major difference between traditional dose-findi...
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| Udgivet i: | Stat Med |
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| Main Authors: | , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2008
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4562497/ https://ncbi.nlm.nih.gov/pubmed/18563789 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/sim.3329 |
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