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A modified toxicity probability interval method for dose-finding trials
BACKGROUND: Building on earlier work, the toxicity probability interval (TPI) method, we present a modified TPI (mTPI) design that is calibration-free for phase I trials. PURPOSE: Our goal is to improve the trial conduct and provide more effective designs while maintaining the simplicity of the orig...
Gardado en:
| Publicado en: | Clin Trials |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2010
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5038924/ https://ncbi.nlm.nih.gov/pubmed/20935021 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1740774510382799 |
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