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Lipoxin A(4) Attenuates Constitutive and TGF-β1–Dependent Profibrotic Activity in Human Lung Myofibroblasts

Idiopathic pulmonary fibrosis (IPF) is a common, progressive, and invariably lethal interstitial lung disease with no effective therapy. The key cell driving the development of fibrosis is the myofibroblast. Lipoxin A(4) (LXA(4)) is an anti-inflammatory lipid, important in the resolution of inflamma...

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Bibliografiske detaljer
Udgivet i:J Immunol
Main Authors: Roach, Katy M., Feghali-Bostwick, Carol A., Amrani, Yassine, Bradding, Peter
Format: Artigo
Sprog:Inglês
Udgivet: AAI 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4560490/
https://ncbi.nlm.nih.gov/pubmed/26276873
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1500936
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