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1,25(OH)(2)D(3) Promotes the Efficacy of CD28 Costimulation Blockade by Abatacept
Inhibition of the CD28:CD80/CD86 T cell costimulatory pathway has emerged as an effective strategy for the treatment of T cell–mediated inflammatory diseases. However, patient responses to CD28-ligand blockade by abatacept (CTLA-4-Ig) in conditions such as rheumatoid arthritis are variable and often...
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| 發表在: | J Immunol |
|---|---|
| Main Authors: | , , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
AAI
2015
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4560489/ https://ncbi.nlm.nih.gov/pubmed/26276872 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1500306 |
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