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Availability of 25-hydroxyvitamin D(3) to antigen presenting cells controls the balance between regulatory and inflammatory T cell responses

1,25-dihydroxyvitamin D(3) (1,25(OH)(2)D(3)), the active form of vitamin D, exerts potent effects on several tissues including cells of the immune system, where it affects T cell activation, differentiation and migration. The circulating, inactive form of vitamin D, 25(OH)D(3), is generally used as...

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Autors principals: Jeffery, Louisa E., Wood, Alice M., Qureshi, Omar S, Hou, Tie Zheng, Gardner, David, Briggs, Zoe, Kaur, Satdip, Raza, Karim, Sansom, David M.
Format: Artigo
Idioma:Inglês
Publicat: 2012
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3504609/
https://ncbi.nlm.nih.gov/pubmed/23087405
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1200786
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