Phase II Trial of Costimulation Blockade With Abatacept for Prevention of Acute GVHD

PURPOSE: Severe (grade 3-4) acute graft-versus-host disease (AGVHD) is a major cause of death after unrelated-donor (URD) hematopoietic cell transplant (HCT), resulting in particularly high mortality after HLA-mismatched transplantation. There are no approved agents for AGVHD prevention, underscorin...

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Publicat a:J Clin Oncol
Autors principals: Watkins, Benjamin, Qayed, Muna, McCracken, Courtney, Bratrude, Brandi, Betz, Kayla, Suessmuth, Yvonne, Yu, Alison, Sinclair, Shauna, Furlan, Scott, Bosinger, Steven, Tkachev, Victor, Rhodes, James, Tumlin, Audrey Grizzle, Narayan, Alexandria, Cribbin, Kayla, Gillespie, Scott, Gooley, Ted A., Pasquini, Marcelo C., Hebert, Kyle, Kapoor, Urvi, Rogatko, Andre, Tighiouart, Mourad, Kim, Sungjin, Bresee, Catherine, Choi, Sung W., Davis, Jeffrey, Duncan, Christine, Giller, Roger, Grimley, Michael, Harris, Andrew C., Jacobsohn, David, Lalefar, Nahal, Norkin, Maxim, Farhadfar, Nosha, Pulsipher, Michael A., Shenoy, Shalini, Petrovic, Aleksandra, Schultz, Kirk R., Yanik, Gregory A., Waller, Edmund K., Levine, John E., Ferrara, James L., Blazar, Bruce R., Langston, Amelia, Horan, John T., Kean, Leslie S.
Format: Artigo
Idioma:Inglês
Publicat: Wolters Kluwer Health 2021
Matèries:
ORIGINAL REPORTS
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8260909/
https://ncbi.nlm.nih.gov/pubmed/33449816
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/JCO.20.01086
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