Phase II Trial of Costimulation Blockade With Abatacept for Prevention of Acute GVHD

PURPOSE: Severe (grade 3-4) acute graft-versus-host disease (AGVHD) is a major cause of death after unrelated-donor (URD) hematopoietic cell transplant (HCT), resulting in particularly high mortality after HLA-mismatched transplantation. There are no approved agents for AGVHD prevention, underscorin...

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Detalhes bibliográficos
Publicado no:J Clin Oncol
Main Authors: Watkins, Benjamin, Qayed, Muna, McCracken, Courtney, Bratrude, Brandi, Betz, Kayla, Suessmuth, Yvonne, Yu, Alison, Sinclair, Shauna, Furlan, Scott, Bosinger, Steven, Tkachev, Victor, Rhodes, James, Tumlin, Audrey Grizzle, Narayan, Alexandria, Cribbin, Kayla, Gillespie, Scott, Gooley, Ted A., Pasquini, Marcelo C., Hebert, Kyle, Kapoor, Urvi, Rogatko, Andre, Tighiouart, Mourad, Kim, Sungjin, Bresee, Catherine, Choi, Sung W., Davis, Jeffrey, Duncan, Christine, Giller, Roger, Grimley, Michael, Harris, Andrew C., Jacobsohn, David, Lalefar, Nahal, Norkin, Maxim, Farhadfar, Nosha, Pulsipher, Michael A., Shenoy, Shalini, Petrovic, Aleksandra, Schultz, Kirk R., Yanik, Gregory A., Waller, Edmund K., Levine, John E., Ferrara, James L., Blazar, Bruce R., Langston, Amelia, Horan, John T., Kean, Leslie S.
Formato: Artigo
Idioma:Inglês
Publicado em: Wolters Kluwer Health 2021
Assuntos:
ORIGINAL REPORTS
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8260909/
https://ncbi.nlm.nih.gov/pubmed/33449816
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/JCO.20.01086
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