Enhanced Expression of Integrin αvβ3 Induced by TGF-β Is Required for the Enhancing Effect of Fibroblast Growth Factor 1 (FGF1) in TGF-β-Induced Epithelial-Mesenchymal Transition (EMT) in Mammary Epithelial Cells

Epithelial-to-mesenchymal transition (EMT) plays a critical role in cancer metastasis, and is regulated by growth factors such as transforming growth factor β (TGF-β) and fibroblast growth factors (FGF) secreted from the stromal and tumor cells. However, the role of growth factors in EMT has not bee...

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Dettagli Bibliografici
Pubblicato in:PLoS One
Autori principali: Mori, Seiji, Kodaira, Moe, Ito, Ayano, Okazaki, Mika, Kawaguchi, Naomasa, Hamada, Yoshinosuke, Takada, Yoshikazu, Matsuura, Nariaki
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2015
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4559424/
https://ncbi.nlm.nih.gov/pubmed/26334633
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0137486
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