TGF-β(1 )induced epithelial to mesenchymal transition (EMT) in human bronchial epithelial cells is enhanced by IL-1β but not abrogated by corticosteroids

BACKGROUND: Chronic persistent asthma is characterized by ongoing airway inflammation and airway remodeling. The processes leading to airway remodeling are poorly understood, and there is increasing evidence that even aggressive anti-inflammatory therapy does not completely prevent this process. We...

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Autores principales: Doerner, Astrid M, Zuraw, Bruce L
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2009
Materias:
Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2774671/
https://ncbi.nlm.nih.gov/pubmed/19857272
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1465-9921-10-100
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