IL-22 contributes to TGF-β1-mediated epithelial-mesenchymal transition in asthmatic bronchial epithelial cells

BACKGROUND: Allergic asthma is characterized by airway inflammation in response to antigen exposure, leading to airway remodeling and lung dysfunction. Epithelial-mesenchymal transition (EMT) may play a role in airway remodeling through the acquisition of a mesenchymal phenotype in airway epithelial...

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Main Authors: Johnson, Jill R, Nishioka, Michiyoshi, Chakir, Jamila, Risse, Paul-André, Almaghlouth, Ibrahim, Bazarbashi, Ahmad N, Plante, Sophie, Martin, James G, Eidelman, David, Hamid, Qutayba
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2013
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4176096/
https://ncbi.nlm.nih.gov/pubmed/24283210
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1465-9921-14-118
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