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TGF-β1 induces human alveolar epithelial to mesenchymal cell transition (EMT)

BACKGROUND: Fibroblastic foci are characteristic features in lung parenchyma of patients with idiopathic pulmonary fibrosis (IPF). They comprise aggregates of mesenchymal cells which underlie sites of unresolved epithelial injury and are associated with progression of fibrosis. However, the cellular...

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Bibliographic Details
Main Authors: Kasai, Hidenori, Allen, Jeremy T, Mason, Roger M, Kamimura, Takashi, Zhang, Zhi
Format: Artigo
Language:Inglês
Published: BioMed Central 2005
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1177991/
https://ncbi.nlm.nih.gov/pubmed/15946381
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1465-9921-6-56
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