Immunostimulatory Defective Viral Genomes from Respiratory Syncytial Virus Promote a Strong Innate Antiviral Response during Infection in Mice and Humans

Human respiratory syncytial virus (RSV) is a major cause of severe respiratory illness in children and susceptible adults. RSV blocks the development of the innate antiviral immune response and can grow to high titers in the respiratory tract. Here we demonstrate that immunostimulatory defective vir...

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Publicat a:PLoS Pathog
Autors principals: Sun, Yan, Jain, Deepika, Koziol-White, Cynthia J., Genoyer, Emmanuelle, Gilbert, Micah, Tapia, Karla, Panettieri, Reynold A., Hodinka, Richard L., López, Carolina B.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2015
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4559413/
https://ncbi.nlm.nih.gov/pubmed/26336095
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1005122
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