Immunostimulatory Defective Viral Genomes from Respiratory Syncytial Virus Promote a Strong Innate Antiviral Response during Infection in Mice and Humans

Human respiratory syncytial virus (RSV) is a major cause of severe respiratory illness in children and susceptible adults. RSV blocks the development of the innate antiviral immune response and can grow to high titers in the respiratory tract. Here we demonstrate that immunostimulatory defective vir...

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Veröffentlicht in:PLoS Pathog
Hauptverfasser: Sun, Yan, Jain, Deepika, Koziol-White, Cynthia J., Genoyer, Emmanuelle, Gilbert, Micah, Tapia, Karla, Panettieri, Reynold A., Hodinka, Richard L., López, Carolina B.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2015
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4559413/
https://ncbi.nlm.nih.gov/pubmed/26336095
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1005122
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