Immunostimulatory Defective Viral Genomes from Respiratory Syncytial Virus Promote a Strong Innate Antiviral Response during Infection in Mice and Humans

Human respiratory syncytial virus (RSV) is a major cause of severe respiratory illness in children and susceptible adults. RSV blocks the development of the innate antiviral immune response and can grow to high titers in the respiratory tract. Here we demonstrate that immunostimulatory defective vir...

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Bibliographic Details
Published in:PLoS Pathog
Main Authors: Sun, Yan, Jain, Deepika, Koziol-White, Cynthia J., Genoyer, Emmanuelle, Gilbert, Micah, Tapia, Karla, Panettieri, Reynold A., Hodinka, Richard L., López, Carolina B.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2015
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4559413/
https://ncbi.nlm.nih.gov/pubmed/26336095
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1005122
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