Immunostimulatory Defective Viral Genomes from Respiratory Syncytial Virus Promote a Strong Innate Antiviral Response during Infection in Mice and Humans

Human respiratory syncytial virus (RSV) is a major cause of severe respiratory illness in children and susceptible adults. RSV blocks the development of the innate antiviral immune response and can grow to high titers in the respiratory tract. Here we demonstrate that immunostimulatory defective vir...

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Publicado en:PLoS Pathog
Main Authors: Sun, Yan, Jain, Deepika, Koziol-White, Cynthia J., Genoyer, Emmanuelle, Gilbert, Micah, Tapia, Karla, Panettieri, Reynold A., Hodinka, Richard L., López, Carolina B.
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2015
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4559413/
https://ncbi.nlm.nih.gov/pubmed/26336095
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1005122
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