A reverse-engineering approach to dissect post-translational modulators of transcription factor’s activity from transcriptional data

BACKGROUND: Transcription factors (TFs) act downstream of the major signalling pathways functioning as master regulators of cell fate. Their activity is tightly regulated at the transcriptional, post-transcriptional and post-translational level. Proteins modifying TF activity are not easily identifi...

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Publicat a:BMC Bioinformatics
Autors principals: Gambardella, Gennaro, Peluso, Ivana, Montefusco, Sandro, Bansal, Mukesh, Medina, Diego L., Lawrence, Neil, di Bernardo, Diego
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2015
Matèries:
Methodology Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4559297/
https://ncbi.nlm.nih.gov/pubmed/26334955
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-015-0700-3
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