Reverse engineering a mouse embryonic stem cell-specific transcriptional network reveals a new modulator of neuronal differentiation

Gene expression profiles can be used to infer previously unknown transcriptional regulatory interaction among thousands of genes, via systems biology ‘reverse engineering’ approaches. We ‘reverse engineered’ an embryonic stem (ES)-specific transcriptional network from 171 gene expression profiles, m...

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Detalhes bibliográficos
Main Authors: De Cegli, Rossella, Iacobacci, Simona, Flore, Gemma, Gambardella, Gennaro, Mao, Lei, Cutillo, Luisa, Lauria, Mario, Klose, Joachim, Illingworth, Elizabeth, Banfi, Sandro, di Bernardo, Diego
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2013
Assuntos:
Computational Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3553984/
https://ncbi.nlm.nih.gov/pubmed/23180766
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gks1136
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