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The impact of microRNAs on transcriptional heterogeneity and gene co-expression across single embryonic stem cells
MicroRNAs act posttranscriptionally to suppress multiple target genes within a cell population. To what extent this multi-target suppression occurs in individual cells and how it impacts transcriptional heterogeneity and gene co-expression remains unknown. Here we used single-cell sequencing combine...
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發表在: | Nat Commun |
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Main Authors: | , , , , , , |
格式: | Artigo |
語言: | Inglês |
出版: |
Nature Publishing Group
2017
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主題: | |
在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5253645/ https://ncbi.nlm.nih.gov/pubmed/28102192 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms14126 |
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