Lipoic acid plays a role in scleroderma: insights obtained from scleroderma dermal fibroblasts

INTRODUCTION: Systemic sclerosis (SSc) is a connective tissue disease characterized by fibrosis of the skin and organs. Increase in oxidative stress and platelet-derived growth factor receptor (PDGFR) activation promote type I collagen (Col I) production, leading to fibrosis in SSc. Lipoic acid (LA)...

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Detalhes bibliográficos
Publicado no:Arthritis Res Ther
Main Authors: Tsou, Pei-Suen, Balogh, Beatrix, Pinney, Adam J, Zakhem, George, Lozier, Ann, Amin, M Asif, Stinson, William A, Schiopu, Elena, Khanna, Dinesh, Fox, David A, Koch, Alisa E
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4558991/
https://ncbi.nlm.nih.gov/pubmed/25123250
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13075-014-0411-6
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