Signaling in Fibrosis: TGF-β, WNT, and YAP/TAZ Converge

Chronic organ injury leads to fibrosis and eventually organ failure. Fibrosis is characterized by excessive synthesis, remodeling, and contraction of extracellular matrix produced by myofibroblasts. Myofibroblasts are the key cells in the pathophysiology of fibrotic disorders and their differentiati...

Full description

Saved in:
Bibliographic Details
Published in:Front Med (Lausanne)
Main Authors: Piersma, Bram, Bank, Ruud A., Boersema, Miriam
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2015
Subjects:
Medicine
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4558529/
https://ncbi.nlm.nih.gov/pubmed/26389119
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmed.2015.00059
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items