Ascorbic acid promotes a TGFβ1‐induced myofibroblast phenotype switch

l‐Ascorbic acid (AA), generally known as vitamin C, is a crucial cofactor for a variety of enzymes, including prolyl‐3‐hydroxylase (P3H), prolyl‐4‐hydroxylase (P4H), and lysyl hydroxylase (LH)‐mediated collagen maturation. Here, we investigated whether AA has additional functions in the regulation o...

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Dades bibliogràfiques
Publicat a:Physiol Rep
Autors principals: Piersma, Bram, Wouters, Olaf Y., de Rond, Saskia, Boersema, Miriam, Gjaltema, Rutger A. F., Bank, Ruud A.
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2017
Matèries:
Original Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5599854/
https://ncbi.nlm.nih.gov/pubmed/28904079
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14814/phy2.13324
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