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Signaling in Fibrosis: TGF-β, WNT, and YAP/TAZ Converge
Chronic organ injury leads to fibrosis and eventually organ failure. Fibrosis is characterized by excessive synthesis, remodeling, and contraction of extracellular matrix produced by myofibroblasts. Myofibroblasts are the key cells in the pathophysiology of fibrotic disorders and their differentiati...
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| Publicado no: | Front Med (Lausanne) |
|---|---|
| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Frontiers Media S.A.
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4558529/ https://ncbi.nlm.nih.gov/pubmed/26389119 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmed.2015.00059 |
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