Schistosome-induced cholangiocyte proliferation and osteopontin secretion correlate with fibrosis and portal hypertension in human and murine schistosomiasis mansoni

Schistosomiasis is a major cause of portal hypertension worldwide. It associates with portal fibrosis that develops during chronic infection. The mechanisms by which the pathogen evokes these host responses remain unclear. We evaluated the hypothesis that schistosome eggs release factors that direct...

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書誌詳細
出版年:Clin Sci (Lond)
主要な著者: Pereira, Thiago A., Syn, Wing-Kin, Machado, Mariana V., Vidigal, Paula V., Resende, Vivian, Voieta, Izabela, Xie, Guanhua, Otoni, Alba, Souza, Márcia M., Santos, Elisângela T., Chan, Isaac S., Trindade, Guilherme V.M., Choi, Steve S., Witek, Rafal P., Pereira, Fausto E., Secor, William E., Andrade, Zilton A., Lambertucci, José Roberto, Diehl, Anna Mae
フォーマット: Artigo
言語:Inglês
出版事項: Portland Press Ltd. 2015
主題:
Original Papers
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4558314/
https://ncbi.nlm.nih.gov/pubmed/26201095
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/CS20150117
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