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Serum osteopontin is a biomarker of severe fibrosis and portal hypertension in human and murine schistosomiasis mansoni

Schistosomiasis is a major cause of fibrosis and portal hypertension. The reason 4–10% of infected subjects develops hepatosplenic schistosomiasis remains unclear. Chronically infected male CBA/J mice reproduce the dichotomic forms of human schistosomiasis. Most mice (80%) develop moderate splenomeg...

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Bibliografiska uppgifter
I publikationen:Int J Parasitol
Huvudupphovsmän: Pereira, Thiago Almeida, Syn, Wing-Kin, Pereira, Fausto E.L., Lambertucci, José Roberto, Secor, William Evan, Diehl, Anna Mae
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2016
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5584370/
https://ncbi.nlm.nih.gov/pubmed/27729270
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ijpara.2016.08.004
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