Schistosome-induced cholangiocyte proliferation and osteopontin secretion correlate with fibrosis and portal hypertension in human and murine schistosomiasis mansoni

Schistosomiasis is a major cause of portal hypertension worldwide. It associates with portal fibrosis that develops during chronic infection. The mechanisms by which the pathogen evokes these host responses remain unclear. We evaluated the hypothesis that schistosome eggs release factors that direct...

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Bibliografiska uppgifter
I publikationen:Clin Sci (Lond)
Huvudupphovsmän: Pereira, Thiago A., Syn, Wing-Kin, Machado, Mariana V., Vidigal, Paula V., Resende, Vivian, Voieta, Izabela, Xie, Guanhua, Otoni, Alba, Souza, Márcia M., Santos, Elisângela T., Chan, Isaac S., Trindade, Guilherme V.M., Choi, Steve S., Witek, Rafal P., Pereira, Fausto E., Secor, William E., Andrade, Zilton A., Lambertucci, José Roberto, Diehl, Anna Mae
Materialtyp: Artigo
Språk:Inglês
Publicerad: Portland Press Ltd. 2015
Ämnen:
Original Papers
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4558314/
https://ncbi.nlm.nih.gov/pubmed/26201095
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/CS20150117
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