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Schistosome-induced cholangiocyte proliferation and osteopontin secretion correlate with fibrosis and portal hypertension in human and murine schistosomiasis mansoni

Schistosomiasis is a major cause of portal hypertension worldwide. It associates with portal fibrosis that develops during chronic infection. The mechanisms by which the pathogen evokes these host responses remain unclear. We evaluated the hypothesis that schistosome eggs release factors that direct...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:Clin Sci (Lond)
Main Authors: Pereira, Thiago A., Syn, Wing-Kin, Machado, Mariana V., Vidigal, Paula V., Resende, Vivian, Voieta, Izabela, Xie, Guanhua, Otoni, Alba, Souza, Márcia M., Santos, Elisângela T., Chan, Isaac S., Trindade, Guilherme V.M., Choi, Steve S., Witek, Rafal P., Pereira, Fausto E., Secor, William E., Andrade, Zilton A., Lambertucci, José Roberto, Diehl, Anna Mae
פורמט: Artigo
שפה:Inglês
יצא לאור: Portland Press Ltd. 2015
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC4558314/
https://ncbi.nlm.nih.gov/pubmed/26201095
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/CS20150117
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