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The Role of Akt Activation in the Response to Chemotherapy in Pancreatic Cancer

The PI3K/Akt signaling pathway is constitutively activated in some pancreatic cancers; when activated, it inhibits chemotherapy-mediated apoptosis. We examined whether Akt activity correlates with apoptotic resistance to chemotherapy in pancreatic cancer. METHODS: A panel of human pancreatic cancer...

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Detalhes bibliográficos
Publicado no:Anticancer Res
Main Authors: Parsons, Colin M., Muilenburg, Diego, Bowles, Tawnya L., Virudachalam, Subbulakshmi, Bold, Richard J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4557882/
https://ncbi.nlm.nih.gov/pubmed/20944098
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