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Role of Autophagy in Apoptotic Regulation by Akt in Pancreatic Cancer

BACKGROUND/AIM: The Akt signaling pathway mediates a potent anti-apoptotic signal in pancreatic cancer and inhibition of this pathway has become an attractive mechanism to increase the efficacy of traditional chemotherapies. Autophagy is a lysosomal catabolic pathway by which eukaryotic cells recycl...

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Bibliografische gegevens
Gepubliceerd in:Anticancer Res
Hoofdauteurs: Muilenburg, Diego, Parsons, Colin, Coates, Jodi, Virudachalam, Subbulakshmi, Bold, Richard J.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2014
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4565513/
https://ncbi.nlm.nih.gov/pubmed/24510992
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