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Pegylated arginine deiminase synergistically increases the cytotoxicity of gemcitabine in human pancreatic cancer

BACKGROUND: Pancreatic ductal adenocarcinoma has proven to be one of the most chemo-resistant among all solid organ malignancies. Several mechanisms of resistance have been described, though few reports of strategies to overcome this chemo-resistance have been successful in restoring sensitivity to...

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Dettagli Bibliografici
Pubblicato in:J Exp Clin Cancer Res
Autori principali: Daylami, Rouzbeh, Muilenburg, Diego J, Virudachalam, Subbulakshmi, Bold, Richard J
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4279680/
https://ncbi.nlm.nih.gov/pubmed/25499121
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-014-0102-9
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