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AKT inhibition is associated with chemosensitisation in the pancreatic cancer cell line MIA-PaCa-2

Activation of the serine/threonine kinase AKT is common in pancreatic cancer; inhibition of which sensitises cells to the apoptotic effect of chemotherapy. Of the various downstream targets of AKT, we examined activation of the NF-κB transcription factor and subsequent transcriptional regulation of...

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Bibliografische gegevens
Hoofdauteurs: Fahy, B N, Schlieman, M, Virudachalam, S, Bold, R J
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group 2003
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2394257/
https://ncbi.nlm.nih.gov/pubmed/12865934
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6601037
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