Inhibition of human pancreatic cancer cell (MIA PaCa-2) growth by cholera toxin and 8-chloro-cAMP in vitro.

The effects of cholera toxin (CT) and 8-chloro-cAMP (8-Cl-cAMP) on cell growth were investigated using two human pancreatic carcinoma cell lines (MIA PaCa-2, Panc-1). CT, which catalyses the ADP ribosylation of Gs, suppresses the proliferation of MIA PaCa-2(PC) cells. CT at the low dose of 0.1 pg ml...

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Hauptverfasser: Ohmura, E., Wakai, K., Isozaki, O., Murakami, H., Onoda, N., Emoto, N., Shizume, K., Tsushima, T., Demura, H., Robins, R. K.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 1993
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1968158/
https://ncbi.nlm.nih.gov/pubmed/8381655
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