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Metabolic Consequences of LDHA inhibition by Epigallocatechin Gallate and Oxamate in MIA PaCa-2 Pancreatic Cancer Cells

Lactate dehydrogenase A (LDHA) is the enzyme that converts pyruvate to lactate and oxidizes the reduced form of nicotinamide adenine dinucleotide (NADH) to NAD(+). Several human cancers including the pancreas display elevated expression of LDHA. Because of its essential role in cancer metabolism, LD...

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Detalhes bibliográficos
Publicado no:Metabolomics
Main Authors: Lu, Qing-Yi, Zhang, Lifeng, Yee, Jennifer K., Go, Vay-Liang W., Lee, Wai-Nang
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4523095/
https://ncbi.nlm.nih.gov/pubmed/26246802
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11306-014-0672-8
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