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Metabolic Consequences of LDHA inhibition by Epigallocatechin Gallate and Oxamate in MIA PaCa-2 Pancreatic Cancer Cells
Lactate dehydrogenase A (LDHA) is the enzyme that converts pyruvate to lactate and oxidizes the reduced form of nicotinamide adenine dinucleotide (NADH) to NAD(+). Several human cancers including the pancreas display elevated expression of LDHA. Because of its essential role in cancer metabolism, LD...
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| Udgivet i: | Metabolomics |
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| Main Authors: | , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2014
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4523095/ https://ncbi.nlm.nih.gov/pubmed/26246802 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11306-014-0672-8 |
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