AKT inhibition is associated with chemosensitisation in the pancreatic cancer cell line MIA-PaCa-2
Activation of the serine/threonine kinase AKT is common in pancreatic cancer; inhibition of which sensitises cells to the apoptotic effect of chemotherapy. Of the various downstream targets of AKT, we examined activation of the NF-κB transcription factor and subsequent transcriptional regulation of...
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| Huvudupphovsmän: | , , , |
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| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
Nature Publishing Group
2003
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2394257/ https://ncbi.nlm.nih.gov/pubmed/12865934 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6601037 |
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